sciCORE is a center for scientific computing at the University of Basel, providing high-performance computing infrastructures and services. In January 2014, sciCORE was formally established as a University core facility, leveraging preexisting infrastructures and know-how at the University of Basel's IT-Services Maia and Biozentrum's [BC]2 life-science HPC environments. sciCORE supports areas of science with advanced computational needs, e.g. computationally intensive simulations or large scale data analysis projects. Currently active projects span a broad spectrum from physics, computational chemistry, life sciences, medicine, economy and others. With the support of the SIB Swiss Institute of Bioinformatics, sciCORE provides advanced scientific-computing consulting and training to the Swiss life-science community.